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Research provides insight on potential impact of obesity on the brain
POSTED 08 Aug 2014 . BY Chris Dodd
Obesity is a major problem throughout the developed world, not least in the US and Europe Credit: Shutterstock.com/bikeriderlondon
Obesity could have an impact on how smart we are, after research conducted on mice showed how fat levels may potentially cloud cognitive processes.

In a study conducted at Georgia Regents University, experts monitored a group of obese mice that housed high levels of a chemical substance known as interleukin 1.

The substance is known to be created from fat cells and can lead to inflammation, which was the case when the researchers observed the brains of the mice, finding that the chemical had managed to seep into the hippocampus – an area in the brain which takes care of both learning capabilities and memory function.

The obese mice tested poorly during cognitive tests, with scientists presuming the levels of interleukin 1 and subsequent inflammation had impacted on the mice’s efficiency.

To back up their initial findings, the scientists decided to conduct a small liposuction procedure on the obese mice to remove fat, which led to the specimens performing a lot better on the same cognitive tests they had taken before the removal of the fat.

The results were solidified as the researchers then placed fat pads inside leaner mice, with the animals performing worse than they had done in their previous brain function tests.

The research also provided an insight towards what exercise can do for the function of the brain, with obese mice placed on a daily exercise regime.

They were then compared to a group of sedentary mice after three months, where results showed that despite remaining the same weight as those that didn't take part in exercise, the obese mice had gained lean muscle and lost fat, while they also began to outperform the non-active mice in cognitive tests.

Obviously, the research into the mice does not necessarily stand as evidence for how the human brain could react, but it does offer further weight to a growing and predominantly accepted argument that exercise can help to improve brain function and general health too.

A number of other findings recently have shown the potential benefits of exercise and physical fitness both on children and adults.

One study has shown that physical condition could have an impact on the academic performance of young people, while another has suggested that exercise should be prescribed to improve the health of older women.

Meanwhile, in a study soon to be published in the September 2014 issue of the Journal of Occupational and Environmental Hygiene, obesity has been shown to have a detrimental impact on the endurance of workers when performing many workplace tasks, for example in factory or industrial settings.
RELATED STORIES
  Accepting obesity as the norm goes against our sector's principles: HCM editor Kate Cracknell


Accepting obesity as something to be catered for, rather than a tide to be turned, would go against everything the health and industry believes in, according to Health Club Management editor Kate Cracknell in her August leader column.
  Exercise should be prescribed to improve health of older women, says new study


Research from the Queensland University of Technology's Institute of Health and Biomedical Innovation suggesting that moderate to high intensity activity could be essential to reducing the risk of death in older women.
  ukactive says new medical guidelines could cause 'surgery first' mentality to obesity crisis


ukactive CEO David Stalker has raised concerns that people are in danger of promoting a ‘surgery first’ mentality to managing obesity-related conditions in the wake of new draft guidelines from the National Institute of Health and Care Excellence (NICE),which is aiming to reduce debilitating weight problems.
  European Court of Justice could define obesity as a disability


The European Court of Justice is considering a test case which could oblige employers to treat obesity as a disability, potentially leaving them with a duty to make adjustments to work environments.
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NEWS
Research provides insight on potential impact of obesity on the brain
POSTED 08 Aug 2014 . BY Chris Dodd
Obesity is a major problem throughout the developed world, not least in the US and Europe Credit: Shutterstock.com/bikeriderlondon
Obesity could have an impact on how smart we are, after research conducted on mice showed how fat levels may potentially cloud cognitive processes.

In a study conducted at Georgia Regents University, experts monitored a group of obese mice that housed high levels of a chemical substance known as interleukin 1.

The substance is known to be created from fat cells and can lead to inflammation, which was the case when the researchers observed the brains of the mice, finding that the chemical had managed to seep into the hippocampus – an area in the brain which takes care of both learning capabilities and memory function.

The obese mice tested poorly during cognitive tests, with scientists presuming the levels of interleukin 1 and subsequent inflammation had impacted on the mice’s efficiency.

To back up their initial findings, the scientists decided to conduct a small liposuction procedure on the obese mice to remove fat, which led to the specimens performing a lot better on the same cognitive tests they had taken before the removal of the fat.

The results were solidified as the researchers then placed fat pads inside leaner mice, with the animals performing worse than they had done in their previous brain function tests.

The research also provided an insight towards what exercise can do for the function of the brain, with obese mice placed on a daily exercise regime.

They were then compared to a group of sedentary mice after three months, where results showed that despite remaining the same weight as those that didn't take part in exercise, the obese mice had gained lean muscle and lost fat, while they also began to outperform the non-active mice in cognitive tests.

Obviously, the research into the mice does not necessarily stand as evidence for how the human brain could react, but it does offer further weight to a growing and predominantly accepted argument that exercise can help to improve brain function and general health too.

A number of other findings recently have shown the potential benefits of exercise and physical fitness both on children and adults.

One study has shown that physical condition could have an impact on the academic performance of young people, while another has suggested that exercise should be prescribed to improve the health of older women.

Meanwhile, in a study soon to be published in the September 2014 issue of the Journal of Occupational and Environmental Hygiene, obesity has been shown to have a detrimental impact on the endurance of workers when performing many workplace tasks, for example in factory or industrial settings.
RELATED STORIES
Accepting obesity as the norm goes against our sector's principles: HCM editor Kate Cracknell


Accepting obesity as something to be catered for, rather than a tide to be turned, would go against everything the health and industry believes in, according to Health Club Management editor Kate Cracknell in her August leader column.
Exercise should be prescribed to improve health of older women, says new study


Research from the Queensland University of Technology's Institute of Health and Biomedical Innovation suggesting that moderate to high intensity activity could be essential to reducing the risk of death in older women.
ukactive says new medical guidelines could cause 'surgery first' mentality to obesity crisis


ukactive CEO David Stalker has raised concerns that people are in danger of promoting a ‘surgery first’ mentality to managing obesity-related conditions in the wake of new draft guidelines from the National Institute of Health and Care Excellence (NICE),which is aiming to reduce debilitating weight problems.
European Court of Justice could define obesity as a disability


The European Court of Justice is considering a test case which could oblige employers to treat obesity as a disability, potentially leaving them with a duty to make adjustments to work environments.
MORE NEWS
Warner Bros Discovery collaborates on upcoming Pompeii attraction
A new immersive attraction designed to transport visitors into the final hours of ancient Pompeii is preparing to open near the world-famous archaeological site in southern Italy.
Bob Rogers hands BRC to long-serving leadership team
Experience design company, BRC Imagination Arts, has completed a transition that sees founder Bob Rogers pass ownership of the business to four long-serving senior executives, while remaining actively involved with the company.
Rainer Maelzer joins Therme Group as chief entertainment officer
Rainer Maelzer, an experiential entertainment innovator, has been appointed chief entertainment officer by Therme Group.
Movie Park Germany reveals new Paramount attraction as part of its 30th anniversary celebrations
Movie Park Germany has opened a new Paramount Pictures-themed attraction as part of its 30th anniversary celebrations, using immersive storytelling and adaptive reuse to reinforce the park’s longstanding “Hollywood in Germany” positioning.
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ProSlide Technology, Inc.

A former national ski team racer, ProSlide® CEO Rick Hunter’s goal has been to integrate the smoot [more...]
Clip 'n Climb

Clip ‘n Climb currently offers facility owners and investors more than 40 colourful and unique Cha [more...]
Vekoma Rides Manufacturing B.V.

Vekoma Rides has a large variety of coasters and attractions. [more...]
Taylor Made Designs

Founded in 1993, Taylor Made Designs supply corporate clothing and brand-enhancing merchandise to [more...]
+ More profiles  
FEATURED SUPPLIER

Iconic Liverpool attraction opens door to new operators
An opportunity to reimagine one of the UK’s most recognisable towers has been formally opened by Rivington Hark, as St Johns Beacon invites operators and partners to shape its next phase. [more...]
CATALOGUE GALLERY
+ More catalogues  
DIRECTORY
+ More directory  
DIARY

 

09-11 Jun 2026

World Sauna Forum 2026

Savutuvan Apaja, Haapaniemi, Finland
23-26 Aug 2026

Elevate Spa Riviera Maya Edition

The Riviera Maya Edition Kanai, Playa del Carmen, Mexico
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
ATTRACTIONS MANAGEMENT NEWS
ATTRACTIONS HANDBOOK
PRINT SUBSCRIPTIONS
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